40 Y/ M WITH CHRONIC LIVER DISEASE

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40 year old male who is a fruit vendor , was brought to the casuality with generalised weakenss and fever since 2 days and excessive sleepiness since 2 days

HOPI:

patient was apparently asymptomatic 20  years back ,5 yrs back he was admitted in alcohol de addiction centre for 2 months and he stopped drinking alcohol for 4 months and then he again started drinking alchohol. 

Now pt c/o generalised weakness and fever since 2 days and excessive sleepiness since 2 days



PAST HISTORY:


N/k/c/o DM,HTN,ASTHMA,TB,EPILEPSY,CAD

K/c/o alcoholic since 20 years

Last binge 4 days ago 

PERSONAL HISTORY: 


Alcoholic since 20 yrs ,daily consumption ( 90 ml)

Diet - mixed 

Sleep- adequate

Bowel and Bladder movements - Regular

General Examination:

Patient is Drowsy, Coharent, co-operative

Pallor - mild

Icterus-present

Clubing-absebt

Kilonychia-absent

Lymphedenopathy- absent

Edema- absent

Febrile-100.8 F

Bp:100/80 mm hg

PR ; 112 bpm regular

Spo2: 98%@RA

SYSTEMIC EXAMINATION: 

Cvs : s1 s2 +

Rs : BAE +

P/A: soft , non tender 

Hepatomegaly +

Flapping Tremors.  

INVESTIGATION: 

CBP - 

HB - 11.4

TLC - 7300

platelet count- 1.5 lakh

Smear - Normocytic normochromic

BGT : A + ( positive) 

APTT :36 sec

PT : 17 sec

INR: 1.2 sec

RBS : 101 mg/dl


LFT :

Total bilirubin : 6.77

Direct bilirubin: 2.98

SGOT: 157

SGPT: 25

ALP : 507

ALBUMIN 3.1

TOTAL PROTEIN : 6.6


RFT : 

Urea -13

creatinine- 0.6

Uric acid - 3.9

calcium- 10.2

Phosphorus- 4.0

potassium - 3.9

Sodium -136

chloride-98



HbsAg - Negative


USG ABDOMEN  ( 7/3/22) : 

Grade 3 fatty liver with mild hepatomegaly with mild caudate lobe hypertrophy


Mild splenomegaly with early parenchymal licer disease

ECG: 

PROVISIONAL DIAGNOSIS: 

Decompensated liver disease with alcohol dependence syndrome ( ? Cirrhosis with portal hypertension )

TREATMENT:

 Inj. Pantop 40 mg iv /od

Inj thiamine 1 amp il

Inj zofer 4 mg iv / ns 

Syrup lactulose 10 ml / po / bd

Tab rifaximin 540 mg / po/ bd

Soap water enema stat

Tab udiliv 300 mg / po / bd

Tab aldactone 25 mg /po /bd

Tab lasix 20 mg /po/ bd 

Tab benxl /po/od

Mcotex gums 

Tab levittacetam 500 mg /po/bd

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